Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542144 | 0.85 | LMNA (0.48) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542288 | 0.82 | MEN1 (0.47) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542158 | 0.81 | MEN1 (0.49) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9540786 | 0.80 | ALOX15 (0.45) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9540800 | 0.79 | ALOX15 (0.47) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL11236957 | 0.75 | CA2 (0.61) | CA2LMNAKDM4EHTTALDH1A1 | |
| SCHEMBL10455127 | 0.75 | LMNA (0.60) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL28446243 | 0.75 | CA2 (0.65) | CA2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL9205403 | 0.74 | MEN1 (0.44) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9540822 | 0.74 | THRB (0.46) | MEN1KMT2AKDM4EHTTAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |