Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568787 | 0.78 | HSD11B1 (0.46) | TSHRSMN1; SMN2ALDH1A1HTTHSD11B1 | |
| SCHEMBL3596359 | 0.73 | NPC1 (0.56) | TSHRNPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL6172162 | 0.72 | GRM5 (0.47) | TP53ALDH1A1 | |
| SCHEMBL8790766 | 0.72 | KMT2A (0.48) | TSHRNPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8791403 | 0.72 | ALDH1A1 (0.49) | TSHRSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8707477 | 0.72 | RAB9A (0.48) | TSHRNPC1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8789847 | 0.72 | DAO (0.33) | NPC1SMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL16795693 | 0.72 | TP53 (0.47) | TSHRNPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL8843434 | 0.71 | HTT (0.57) | TSHRNPC1SMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL8791633 | 0.71 | CYP2A6 (0.38) | TSHRALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5043574-A | — | — | None | — | — | JP | disclosed |
| JP-H0543574-A | HETERO RING-SUBSTITUTED TETRAZOLE-1-ACETIC ACID DERIVATIVE | WAKAMOTO PHARMACEUT CO LTD | 1993-02-23 | — | — | JP | disclosed |