Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400558 | 0.84 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9400646 | 0.78 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL4011471 | 0.77 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL30312308 | 0.77 | ALDH1A1 (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL5260301 | 0.77 | VDR (0.49) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29540314 | 0.77 | GABRA1 (0.70) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL155013 | 0.77 | GABRA1 (0.70) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL5653778 | 0.76 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9543434 | 0.75 | KIF11 (0.39) | MAPTALDH1A1KDM4EGAACA12 | |
| SCHEMBL26630415 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |