Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963382 | 0.93 | PDE10A (0.37) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8963379 | 0.93 | PDE10A (0.37) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8964261 | 0.89 | OPRM1 (0.40) | PDE10ANPC1RAB9ASMN1; SMN2OPRM1 | |
| SCHEMBL8964263 | 0.89 | OPRM1 (0.40) | PDE10ANPC1RAB9ASMN1; SMN2OPRM1 | |
| SCHEMBL8962756 | 0.83 | SMN1; SMN2 (0.35) | NPC1RAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL8962748 | 0.83 | SMN1; SMN2 (0.35) | NPC1RAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL8963100 | 0.81 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL8963105 | 0.81 | RAB9A (0.41) | NPC1RAB9ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL12151773 | 0.80 | PDE10A (0.43) | PDE10ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8963194 | 0.80 | CSF1R (0.38) | PDE10AL3MBTL1IDO1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |