Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921313 | 0.88 | CCKBR (0.44) | CCKBRCYP2C19RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8398527 | 0.84 | CCKBR (0.48) | CCKBRRAB9AALDH1A1 | |
| SCHEMBL8921786 | 0.84 | CCKBR (0.62) | CCKBRSMN1; SMN2GAA | |
| SCHEMBL8920848 | 0.77 | CYP2C19 (0.47) | CCKBRCYP2C19RAB9A | |
| SCHEMBL9544115 | 0.76 | CYP2C19 (0.46) | CYP2C19RAB9AALDH1A1GAA | |
| SCHEMBL9541395 | 0.75 | CCKBR (0.67) | CCKBR | |
| SCHEMBL9541285 | 0.75 | CCKBR (0.79) | CCKBR | |
| SCHEMBL9542994 | 0.74 | CCKBR (0.65) | CCKBRSMN1; SMN2 | |
| SCHEMBL9540184 | 0.74 | CYP2C19 (0.43) | CCKBRCYP2C19 | |
| SCHEMBL9540219 | 0.74 | CCKBR (0.47) | CCKBRCYP2C19PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |