Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375258 | 0.87 | SIRT2 (0.49) | HTR1ADRD2SSTR1SSTR2SSTR4 | |
| SCHEMBL7809511 | 0.73 | PDE4B (0.50) | HTR1AMAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9733015 | 0.70 | HTR2A (0.58) | SSTR1SSTR2SSTR4SSTR3SMN1; SMN2 | |
| SCHEMBL8335507 | 0.69 | SIRT2 (0.56) | HTR1ADRD2MAPTSMN1; SMN2LMNA | |
| SCHEMBL8316997 | 0.67 | SIRT2 (0.53) | SSTR1SSTR2SSTR4SSTR3TACR1 | |
| SCHEMBL5879137 | 0.67 | HTR1D (0.49) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL9402457 | 0.67 | PIK3CA (0.46) | TACR1MAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL9583723 | 0.66 | MEN1 (0.46) | SSTR1SSTR2SSTR4SSTR3MEN1 | |
| SCHEMBL8335104 | 0.65 | HTR1A (0.50) | HTR1ADRD2MAPTSMN1; SMN2LMNA | |
| SCHEMBL5432612 | 0.65 | GPR84 (0.66) | HTR1AMAPTMEN1KMT2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | claimed |