Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543455 | 0.92 | POLB (0.39) | DRD2DRD4HTR1AHTR7MAPT | |
| SCHEMBL9543221 | 0.90 | DRD2 (0.35) | DRD2DRD4HTR1AHTR7OPRM1 | |
| SCHEMBL9543406 | 0.89 | PTPN1 (0.38) | — | |
| SCHEMBL9543510 | 0.88 | ALDH1A1 (0.43) | DRD2DRD4OXTRAVPR1A | |
| SCHEMBL9543363 | 0.88 | DRD2 (0.41) | DRD2DRD4MAPTLMNAOPRM1 | |
| SCHEMBL9542649 | 0.87 | PREP (0.39) | — | |
| SCHEMBL9542741 | 0.87 | CFTR (0.37) | MAPTOXTRAVPR1AOPRM1 | |
| SCHEMBL9544819 | 0.86 | DRD4 (0.38) | DRD2DRD4 | |
| SCHEMBL9543247 | 0.86 | POLB (0.39) | HTR1AHTR7LMNA | |
| SCHEMBL9544446 | 0.84 | HDAC8 (0.36) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | claimed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |