Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542239 | 0.84 | TSHR (0.42) | POLBSLC6A2SLC6A4SLC6A9MAPT | |
| SCHEMBL9318982 | 0.84 | LMNA (0.51) | POLBSLC6A2SLC6A4CNR2MAPT | |
| SCHEMBL9540766 | 0.83 | SLC6A2 (0.44) | POLBSLC6A2SLC6A4SLC6A9CNR2 | |
| SCHEMBL10453097 | 0.82 | SLC6A9 (0.51) | POLBSLC6A2SLC6A4SLC6A9MAPT | |
| SCHEMBL9542226 | 0.80 | TRPM8 (0.47) | SLC6A2SLC6A4SLC6A9MAPTTRPM8 | |
| SCHEMBL12352851 | 0.77 | TSHR (0.50) | POLBCNR2MAPTNPC1RAB9A | |
| SCHEMBL12917871 | 0.75 | ALDH1A1 (0.58) | POLBSLC6A9CNR2MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL8843682 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A9CNR2MAPT | |
| SCHEMBL9540784 | 0.75 | MEN1 (0.47) | POLBSLC6A2SLC6A4SLC6A9MAPT | |
| SCHEMBL10453321 | 0.75 | MAPT (0.50) | SLC6A2SLC6A4SLC6A9MAPTTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |