Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540877 | 0.86 | SLC6A9 (0.47) | SLC6A2SLC6A4SLC6A9CNR2SLC6A3 | |
| SCHEMBL9543443 | 0.84 | TSHR (0.43) | SLC6A2SLC6A4SLC6A9MAPTMEN1 | |
| SCHEMBL9215078 | 0.83 | MEN1 (0.56) | SLC6A2SLC6A4CNR2CHRNA1CHRNG | |
| SCHEMBL9543463 | 0.83 | POLB (0.44) | SLC6A2SLC6A4SLC6A9CNR2MAPT | |
| SCHEMBL10453097 | 0.83 | SLC6A9 (0.51) | SLC6A2SLC6A4SLC6A9MAPTMEN1 | |
| SCHEMBL9540784 | 0.82 | MEN1 (0.47) | SLC6A2SLC6A4SLC6A9MAPTMEN1 | |
| SCHEMBL9540773 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A9MAPTMEN1 | |
| SCHEMBL1355453 | 0.79 | HSD11B1 (0.53) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL12352851 | 0.78 | TSHR (0.50) | CNR2MAPTMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL8843682 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A9CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |