Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861313 | 0.93 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7860005 | 0.89 | ABCB1 (0.51) | ABCB1APPMTNR1AMEN1KMT2A | |
| Butane SCHEMBL9544535 | 0.88 | ABCB1 (0.42) | SLC6A4HTR2CHTR2BABCB1KDM4E | |
| SCHEMBL7861112 | 0.80 | ATM (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19APP | |
| SCHEMBL7861235 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAPTPN1MRGPRX4 | |
| SCHEMBL7860078 | 0.74 | ALDH1A1 (0.47) | ABCB1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7854387 | 0.72 | ALDH1A1 (0.45) | KDM4EALDH1A1LMNAMRGPRX4 | |
| SCHEMBL6713228 | 0.71 | PPARG (0.53) | ALDH1A1LMNA | |
| SCHEMBL6713441 | 0.69 | RXRA (0.53) | KDM4EALDH1A1LMNAMRGPRX4 | |
| SCHEMBL9206341 | 0.68 | KMT2A (0.48) | KDM4EALDH1A1CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016051-A1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-19 | — | — | WO | disclosed |