Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860078 | 0.85 | ALDH1A1 (0.47) | KMT2AL3MBTL1GLAALDH1A1RECQL | |
| SCHEMBL7861235 | 0.83 | ALDH1A1 (0.48) | L3MBTL1TDP1MAPK1LMNAALDH1A1 | |
| SCHEMBL9641284 | 0.77 | KMT2A (0.41) | KMT2AMEN1GAAL3MBTL1CYP1A2 | |
| SCHEMBL9199837 | 0.77 | ALDH1A1 (0.47) | L3MBTL1TDP1LMNAALDH1A1RECQL | |
| SCHEMBL9209376 | 0.77 | L3MBTL1 (0.40) | KMT2AMEN1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL3102952 | 0.74 | MAPT (0.49) | KMT2AMEN1GAAL3MBTL1CYP1A2 | |
| SCHEMBL11285420 | 0.74 | MAPT (0.46) | KMT2AMEN1GAAL3MBTL1CYP1A2 | |
| SCHEMBL28753087 | 0.73 | MMP8 (0.57) | KMT2AMEN1GAAL3MBTL1CYP1A2 | |
| SCHEMBL29277093 | 0.73 | MAPT (0.45) | KMT2AMEN1GAAL3MBTL1CYP1A2 | |
| SCHEMBL5381952 | 0.73 | MMP8 (0.47) | KMT2AMEN1GAAL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| CN-1028100-C | Process for preparing phenoxy-heterocyclic compounds | MIDICINE INST CHINESE MEDICAL (CN) | 1995-04-05 | — | — | CN | disclosed |
| CN-1051039-A | Phenoxy group-heterogeneous ring compound | MERRELL DOW PHARMA (US) | 1991-05-01 | — | — | CN | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |