Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861235 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RECQLMMP8L3MBTL1MAPT | |
| SCHEMBL9206341 | 0.85 | KMT2A (0.48) | ALDH1A1RECQLMMP8KMT2AGLA | |
| SCHEMBL9199837 | 0.82 | ALDH1A1 (0.47) | ALDH1A1RECQLMMP8PIN1PPID | |
| SCHEMBL16865453 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RECQLMMP8TAAR1THRB | |
| SCHEMBL7431853 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RECQLMMP8ABCB1TAAR1 | |
| SCHEMBL7860005 | 0.75 | ABCB1 (0.51) | ABCB1KMT2AGLAL3MBTL1FFAR1 | |
| SCHEMBL7854590 | 0.75 | TDP1 (0.47) | ALDH1A1MMP8ABCB1PPARGPTGES | |
| SCHEMBL7854387 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7861112 | 0.74 | ATM (0.45) | ALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL20350605 | 0.74 | MMP8 (0.58) | ALDH1A1RECQLMMP8TAAR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625969-B1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMA INC (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5407954-A | Serotonin antagonism; treats depression, anxiety, hypertension and migraine headaches | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0625969-A1 | ARYLALKOXYPHENOXY-IMIDAZOLINE COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5216008-A | Antidepressant, anxiolytic, hypotensive and also treats migraine headaches | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-01 | — | — | US | disclosed |