Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545171 | 0.79 | P2RX7 (0.56) | HDAC6P2RX7EGFRKDRCCNE2 | |
| SCHEMBL29427431 | 0.77 | POLB (0.50) | FPR2KDM4EALDH1A1HDAC6F2 | |
| SCHEMBL13807679 | 0.77 | DAPK1 (0.42) | KDM4EALDH1A1EGFRSRCKDR | |
| SCHEMBL1919833 | 0.76 | FPR2 (0.35) | FPR2KDM4EALDH1A1ADORA2AHDAC6 | |
| SCHEMBL4014331 | 0.73 | HDAC6 (0.41) | FPR2KDM4EALDH1A1HDAC6P2RX7 | |
| SCHEMBL2063606 | 0.72 | ADORA2A (0.64) | ADORA2AP2RX7CCNE1CDK2DNMT3A | |
| SCHEMBL24476420 | 0.71 | AMPD1 (0.44) | ALDH1A1ADORA2ASMN1; SMN2LMNA | |
| SCHEMBL4007105 | 0.71 | ADK (0.40) | FPR2KDM4EALDH1A1HDAC6P2RX7 | |
| SCHEMBL28654272 | 0.71 | AMPD1 (0.44) | ALDH1A1ADORA2ASMN1; SMN2LMNA | |
| SCHEMBL28657763 | 0.71 | AMPD1 (0.44) | ALDH1A1ADORA2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |