Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89736 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL9805485 | 0.92 | LMNA (0.32) | LMNASLC6A6CYP2C19BLMGLRA1 | |
| SCHEMBL27407885 | 0.92 | LMNA (0.32) | LMNASLC6A6CYP2C19BLMGLRA1 | |
| SCHEMBL28514581 | 0.92 | LMNA (0.32) | LMNASLC6A6CYP2C19BLMGLRA1 | |
| SCHEMBL28762849 | 0.92 | LMNA (0.32) | LMNASLC6A6CYP2C19BLMGLRA1 | |
| Glycerin SCHEMBL18730258 | 0.81 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL28578751 | 0.76 | ALDH1A1 (0.33) | LMNA | |
| Sulfuric Acid SCHEMBL27480157 | 0.76 | CA5A (0.35) | LMNASLC6A6CYP2C19BLMGLRA1 | |
| SCHEMBL9017197 | 0.75 | LMNA (0.36) | LMNASLC6A6CYP2C19BLMCA2 | |
| SCHEMBL362989 | 0.73 | TSHR (0.38) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016180-A2 | SEQUENCES FOR A 90K TUMOR-ASSOCIATED ANTIGEN, IMMUNOREGULIN-95 (IR-95) | MAX PLANCK GESELLSCHAFT (DE) | 1993-08-19 | — | — | WO | disclosed |