Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16042097 | 0.86 | TK1 (0.42) | TK2TK1LMNAADRA1A | |
| SCHEMBL1740177 | 0.85 | LMNA (0.47) | TK2PYGMLMNASMN1; SMN2ALOX12 | |
| SCHEMBL5614068 | 0.84 | PYGM (0.50) | TK2TK1PYGMLMNASMN1; SMN2 | |
| SCHEMBL27271553 | 0.83 | TK2 (0.40) | TK2TK1PYGMLMNASMN1; SMN2 | |
| SCHEMBL22616910 | 0.81 | LMNA (0.37) | TK2TK1PYGMLMNASMN1; SMN2 | |
| SCHEMBL3978670 | 0.80 | PYGM (0.37) | TK2TK1PYGMLMNASMN1; SMN2 | |
| SCHEMBL8951912 | 0.77 | TK1 (0.33) | TK2TK1PYGMLMNASMN1; SMN2 | |
| SCHEMBL5201948 | 0.77 | TK1 (0.41) | TK2TK1LMNAADRA1A | |
| SCHEMBL8951921 | 0.77 | RNASE1 (0.36) | TK2PYGMLMNASMN1; SMN2 | |
| SCHEMBL27271548 | 0.77 | TK2 (0.36) | TK2TK1PYGMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017651-A2 | ANTIVIRAL NUCLEOSIDE ANALOGUES, THEIR PRODUCTION AND USE | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 1993-09-16 | — | — | WO | disclosed |