Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12718264 | 0.79 | SIGMAR1 (0.37) | SIGMAR1OPRK1DRD2DRD3HTR4 | |
| SCHEMBL10238597 | 0.77 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL16767776 | 0.77 | SIGMAR1 (0.38) | SIGMAR1OPRK1DRD2DRD3 | |
| SCHEMBL9877216 | 0.76 | NCF1 (0.39) | SIGMAR1DRD2DRD3HTR4 | |
| SCHEMBL11445829 | 0.76 | SIGMAR1 (0.37) | SIGMAR1DRD2DRD3HTR4 | |
| SCHEMBL22308320 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL4014571 | 0.72 | ADORA2A (0.33) | — | |
| SCHEMBL16510983 | 0.71 | GNAO1 (0.41) | SIGMAR1DRD2DRD3 | |
| SCHEMBL28205065 | 0.71 | NCF1 (0.32) | — | |
| SCHEMBL27076939 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020813-A1 | 1,3,-PROPANEDIAMINE DERIVATIVES HAVING PROTEIN KINASE C INHIBITORY ACTIVITY | SPHNIX PHARMACEUTICALS CORPORATION (US) | 1993-10-28 | — | — | WO | disclosed |