Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9545425 | 0.82 | HTR1A (0.64) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL9844900 | 0.76 | HTR1A (0.88) | HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL6754644 | 0.74 | HTR1A (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6582012 | 0.73 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| Acetic Acid SCHEMBL9366531 | 0.73 | HTR1A (0.61) | HTR1ADRD2 | |
| SCHEMBL6577718 | 0.73 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| SCHEMBL6582852 | 0.73 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1D | |
| Acetic Acid SCHEMBL9361787 | 0.72 | HTR1A (0.61) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10557669 | 0.72 | ALDH1A1 (0.69) | HTR1AADRA1BADRA1AADRA1DDRD2 | |
| SCHEMBL6581749 | 0.72 | ADRA1B (1.00) | HTR1AADRA1BADRA1AADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021179-A1 | NOVEL AMIDOALKYL- AND IMIDOALKYL-PIPERAZINES | AKTIEBOLAGET ASTRA (SE) | 1993-10-28 | — | — | WO | disclosed |