Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038679 | 0.87 | CCR1 (0.41) | HCAR1GRM5LMNA | |
| SCHEMBL10461699 | 0.86 | PTGS2 (0.43) | HCAR1 | |
| SCHEMBL9865677 | 0.82 | HCAR1 (0.36) | HCAR1HTR1DHTR1BHTR1FCA2 | |
| SCHEMBL28598101 | 0.81 | SYK (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL9866318 | 0.80 | ALDH1A1 (0.36) | HCAR1LMNASMN1; SMN2 | |
| SCHEMBL28994100 | 0.80 | POLB (0.34) | HCAR1 | |
| SCHEMBL10745662 | 0.80 | TXNRD1 (0.34) | HCAR1GRM5HTR1DHTR1BHTR1F | |
| SCHEMBL9866531 | 0.80 | POLB (0.36) | HCAR1LMNASMN1; SMN2 | |
| SCHEMBL9867665 | 0.79 | KEAP1 (0.43) | CA2CA12LMNACA1CA9 | |
| SCHEMBL9867638 | 0.78 | FFAR4 (0.34) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |