SCHEMBL9545971

SCHEMBL9545971

CCCC[Si](CCCC)(CCCC)O[Si]O[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
TSHR P16473 2/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907072 0.90 TSHR (0.40) LMNATSHRTHRB
SCHEMBL828184 0.74 TSHR (0.36) TSHR
SCHEMBL5940456 0.73 TSHR (0.38) LMNATSHRTHRB
SCHEMBL537511 0.71 LMNA (0.37) LMNATSHRTHRB
SCHEMBL25404161 0.70 LMNA (0.30) LMNATSHR
SCHEMBL11598761 0.69 TSHR (0.33) LMNATSHRTHRB
SCHEMBL17088158 0.69 TSHR (0.33) LMNATSHRTHRB
SCHEMBL707567 0.69 LMNA (0.35) LMNATSHRTHRB
SCHEMBL23549404 0.69 ADRB2 (0.35) LMNATSHRTHRB
SCHEMBL703661 0.69 LMNA (0.35) LMNATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254553-B1 OPTICAL RECORDING MEDIUM HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-01-13 EP disclosed