SCHEMBL9546098

SCHEMBL9546098

C=C(CC(F)(F)F)C(=O)OCC(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9546008 0.86 HTT (0.45) TET2HTT
SCHEMBL906414 0.81
SCHEMBL9545989 0.80 TSHR (0.35) HTT
SCHEMBL2527318 0.79 HTT (0.32) HTT
SCHEMBL6053875 0.79
SCHEMBL1681694 0.79 ALOX15 (0.34) TET2
SCHEMBL9546019 0.78 ALDH1A1 (0.37) HTT
SCHEMBL26754169 0.78 TET2 (0.31) TET2HTT
SCHEMBL9546037 0.77 TSHR (0.42)
SCHEMBL9578307 0.77 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed
US-5235013-A Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester CIBA-GEIGY CORPORATION 1993-08-10 US disclosed