Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL9547295 | 0.91 | ACHE (0.34) | MEN1KMT2AACHEHRH4HRH3 | |
| SCHEMBL21055715 | 0.85 | THRB (0.41) | ACHEHRH4HRH3ERN1CASP1 | |
| SCHEMBL13055388 | 0.84 | MAPT (0.42) | MEN1KMT2AACHEHRH4HRH3 | |
| SCHEMBL19258784 | 0.84 | TSHR (0.47) | MEN1KMT2AACHEHRH4HRH3 | |
| SCHEMBL21123112 | 0.81 | ACHE (0.33) | MEN1KMT2AACHEHRH4HRH3 | |
| SCHEMBL21693833 | 0.80 | ACHE (0.40) | MEN1KMT2AACHE | |
| SCHEMBL586950 | 0.80 | THRB (0.42) | MEN1KMT2AACHEHRH4HRH3 | |
| SCHEMBL176184 | 0.80 | CYP3A4 (0.43) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL3676772 | 0.79 | TGM2 (0.46) | ACHEERN1 | |
| SCHEMBL2006530 | 0.79 | CHRNB2 (0.42) | MEN1KMT2AACHEHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |