Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547223 | 0.91 | MEN1 (0.36) | ACHEHRH4HRH3MEN1KMT2A | |
| Acetonitrile SCHEMBL9547281 | 0.83 | CHRNB2 (0.40) | ACHEMEN1KMT2AERN1TSHR | |
| SCHEMBL21055715 | 0.79 | THRB (0.41) | ACHEHRH4HRH3ERN1TSHR | |
| Acetonitrile SCHEMBL9547113 | 0.79 | HRH4 (0.32) | ACHEHRH4HRH3ERN1 | |
| SCHEMBL21123112 | 0.76 | ACHE (0.33) | ACHEHRH4HRH3MEN1KMT2A | |
| SCHEMBL13055388 | 0.76 | MAPT (0.42) | ACHEHRH4HRH3MEN1KMT2A | |
| SCHEMBL19258784 | 0.76 | TSHR (0.47) | ACHEHRH4HRH3MEN1KMT2A | |
| SCHEMBL8868991 | 0.75 | MAPT (0.41) | MEN1KMT2ATDP1ERN1TSHR | |
| Acetonitrile SCHEMBL9547088 | 0.75 | MAPT (0.39) | MEN1KMT2ATDP1TSHRMAPT | |
| SCHEMBL21693833 | 0.75 | ACHE (0.40) | ACHEMEN1KMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |