Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006530 | 0.89 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| Acetonitrile SCHEMBL9547295 | 0.83 | ACHE (0.34) | ACHEMEN1KMT2AERN1TSHR | |
| SCHEMBL13055388 | 0.80 | MAPT (0.42) | ACHEMEN1KMT2AERN1TSHR | |
| SCHEMBL8868991 | 0.79 | MAPT (0.41) | MEN1KMT2AERN1TSHRMAPT | |
| SCHEMBL15809690 | 0.79 | ACHE (0.46) | ACHEMEN1KMT2AERN1 | |
| Acetonitrile SCHEMBL9547088 | 0.79 | MAPT (0.39) | MEN1KMT2ATSHRMAPTCACNA1B | |
| Acetonitrile SCHEMBL9547113 | 0.77 | HRH4 (0.32) | ACHEERN1BRD4 | |
| SCHEMBL4458941 | 0.77 | ACHE (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL991007 | 0.76 | ACHE (0.51) | ACHEERN1 | |
| SCHEMBL14458906 | 0.76 | ACHE (0.51) | ACHEERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |