Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20336492 | 0.93 | HRH4 (0.34) | HRH4HRH3ERN1ACHEBRD4 | |
| SCHEMBL13866348 | 0.80 | MEN1 (0.31) | — | |
| Acetonitrile SCHEMBL9547295 | 0.79 | ACHE (0.34) | HRH4HRH3ERN1ACHE | |
| SCHEMBL9697777 | 0.78 | — | — | |
| SCHEMBL8214522 | 0.77 | BACE1 (0.31) | — | |
| Acetonitrile SCHEMBL9547281 | 0.77 | CHRNB2 (0.40) | ERN1ACHEBRD4 | |
| SCHEMBL15166635 | 0.74 | ZDHHC20 (0.42) | — | |
| SCHEMBL1143295 | 0.72 | TDP1 (0.49) | — | |
| SCHEMBL9698992 | 0.72 | — | — | |
| SCHEMBL26121759 | 0.72 | MCL1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |