Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779541 | 0.84 | TRPM8 (0.51) | NPSR1LMNACYP3A4TRPM8HSD17B1 | |
| SCHEMBL22917037 | 0.84 | LMNA (0.53) | NPSR1LMNACYP3A4TRPM8HSD17B1 | |
| SCHEMBL1954826 | 0.82 | SIGMAR1 (0.44) | NPSR1LMNACYP3A4TRPM8HSD17B1 | |
| SCHEMBL12550525 | 0.79 | ALDH1A1 (0.53) | LMNACYP3A4TRPM8HSD17B1HSD17B2 | |
| SCHEMBL23031991 | 0.79 | LMNA (0.49) | NPSR1LMNACYP3A4TRPM8TSHR | |
| SCHEMBL5396721 | 0.79 | SIGMAR1 (0.42) | NPSR1LMNACYP3A4TRPM8HSD17B1 | |
| SCHEMBL11219021 | 0.79 | TRPM8 (0.47) | NPSR1LMNATRPM8HSD17B1HSD17B2 | |
| SCHEMBL2092543 | 0.79 | TRPM8 (0.51) | NPSR1LMNACYP3A4TRPM8TSHR | |
| SCHEMBL23032197 | 0.79 | CYP3A4 (0.43) | NPSR1LMNACYP3A4TRPM8HSD17B1 | |
| SCHEMBL30375032 | 0.77 | TP53 (0.59) | NPSR1LMNACYP3A4TRPM8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194660-A | Processes for producing carbamates and isocyanates | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0083096-B1 | PRODUCTION OF URETHANE COMPOUNDS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-02-25 | — | — | EP | disclosed |
| US-4621149-A | PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0083096-A2 | Production of urethane compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-06 | — | — | EP | disclosed |