Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092543 | 0.90 | TRPM8 (0.51) | TRPM8LMNACYP3A4TEAD1KMT2A | |
| SCHEMBL9547533 | 0.84 | NPSR1 (0.46) | TRPM8LMNACYP3A4TP53HSD17B1 | |
| SCHEMBL7869606 | 0.83 | TRPM8 (0.40) | TRPM8LMNAKMT2AHSD17B1HSD17B2 | |
| SCHEMBL22917037 | 0.82 | LMNA (0.53) | TRPM8LMNACYP3A4KMT2AHSD17B1 | |
| SCHEMBL11219021 | 0.81 | TRPM8 (0.47) | TRPM8LMNAKMT2AHSD17B1HSD17B2 | |
| SCHEMBL28333244 | 0.81 | ALDH1A1 (0.46) | TRPM8LMNACYP3A4KMT2ATP53 | |
| SCHEMBL1029152 | 0.80 | TRPM8 (0.50) | TRPM8LMNAKMT2AHSD17B1HSD17B2 | |
| SCHEMBL1954826 | 0.80 | SIGMAR1 (0.44) | TRPM8LMNACYP3A4TP53HSD17B1 | |
| SCHEMBL8187602 | 0.80 | TRPM8 (0.50) | TRPM8LMNACYP3A4TEAD1KMT2A | |
| Benzene SCHEMBL28335658 | 0.80 | TRPM8 (0.50) | TRPM8LMNAKMT2AHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2378601-B1 | ELECTROLYTE CONTAINING A EUTECTIC MIXTURE AND A SPECIFIC NITRILE COMPOUND, AND ELECTROCHEMICAL DEVICE COMPRISING THE SAME | LG CHEMICAL LTD (KR) | 2016-03-30 | — | — | EP | claimed |
| US-9567307-B2 | Amination of aryl alcohol derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-14 | — | — | US | disclosed |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012094622-A2 | AMINATION OF ARYL ALCOHOL DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-12 | — | — | WO | disclosed |
| EP-0525197-B1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOGS | SHIONOGI & CO (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5319100-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5319099-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0525197-A1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOG | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | SULT2A1, SULT1A1, ADH5 | TRPM8 4783/4885LMNA 2947/4885CYP3A4 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.