Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9005130 | 0.84 | HSD11B1 (0.31) | HSD11B1 | |
| Thiocyanic Acid SCHEMBL9004793 | 0.75 | — | — | |
| SCHEMBL7907713 | 0.75 | MEN1 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL10384257 | 0.73 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL10384331 | 0.71 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL9547761 | 0.66 | HTR2C (0.31) | HSD11B1 | |
| Thiocyanic Acid SCHEMBL9004773 | 0.63 | — | — | |
| Trifluoroacetic Acid SCHEMBL7937712 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL30626928 | 0.60 | HSD11B1 (0.42) | HSD11B1NOTUM | |
| SCHEMBL2295972 | 0.60 | HSD11B1 (0.42) | HSD11B1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256981-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | claimed |
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | claimed |