Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiocyanic Acid SCHEMBL9004773 | 0.90 | — | — | |
| Trifluoroacetic Acid SCHEMBL7937712 | 0.87 | ALDH1A1 (0.32) | KDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9004729 | 0.80 | CES2 (0.35) | KDM4EALDH1A1 | |
| Fluoride Ion SCHEMBL9004749 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9547759 | 0.71 | HSD11B1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2399293 | 0.70 | — | — | |
| SCHEMBL8717849 | 0.66 | — | — | |
| Thiocyanic Acid SCHEMBL9004793 | 0.64 | — | — | |
| SCHEMBL7907713 | 0.64 | MEN1 (0.30) | — | |
| SCHEMBL9004769 | 0.63 | HSD11B1 (0.31) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| US-4960746-A | A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |