SCHEMBL9547840

SCHEMBL9547840

C=CCOC(=O)NCCOc1ccc(Oc2cccc(Cl)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.45
KLKB1 P03952 1/20 0.45
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
GAA P10253 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HTT P42858 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GLA P06280 1/20 0.41
CASP1 P29466 2/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747803 0.87 RAB9A (0.53) RAB9ANPC1GAAHTTSMN1; SMN2
SCHEMBL8966413 0.85 FAAH (0.53) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL9668206 0.84 FAAH (0.55) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL9665380 0.83 FAAH (0.53) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL9163588 0.83 LMNA (0.47) MEN1KMT2ARAB9ANPC1GAA
SCHEMBL9165467 0.82 LMNA (0.43) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL9668317 0.82 HTT (0.58) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL8966388 0.81 DRD2 (0.55) FAAHKLKB1MEN1KMT2ARAB9A
SCHEMBL9747145 0.81 MAPT (0.40) MEN1KMT2ARAB9ANPC1GAA
SCHEMBL10828192 0.77 DRD2 (0.57) FAAHKLKB1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5192803-A Insecticides, miticides, larvicides, ovicides CIBA-GEIGY CORPORATION (US) 1993-03-09 US disclosed
US-5166153-A Insecticides or miticides CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed