SCHEMBL9747145

SCHEMBL9747145

C=CCOC(=O)NCCOc1ccc(Oc2cc(F)cc(F)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
CASP1 P29466 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 2/20 0.38
RAB9A P51151 2/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
BRD4 O60885 1/20 0.38
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
LMNA P02545 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KAT6A Q92794 1/20 0.36
LTA4H P09960 1/20 0.36
NPC1 O15118 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747803 0.85 RAB9A (0.53) MAPTL3MBTL1CASP1SMN1; SMN2HTT
SCHEMBL7191257 0.84 L3MBTL1 (0.48) MAPTL3MBTL1SMN1; SMN2RAB9AGLA
SCHEMBL9547868 0.82 MTNR1A (0.49) MAPTL3MBTL1SMN1; SMN2RAB9AMTNR1A
SCHEMBL9547905 0.81 LMNA (0.43) MAPTL3MBTL1SMN1; SMN2HTTRAB9A
SCHEMBL9547840 0.81 FAAH (0.45) MAPTL3MBTL1CASP1SMN1; SMN2HTT
SCHEMBL9163271 0.79 PPARA (0.42) RAB9ALMNAMEN1KMT2AALDH1A1
SCHEMBL11034079 0.75 L3MBTL1 (0.49) MAPTL3MBTL1CASP1SMN1; SMN2RAB9A
SCHEMBL31437081 0.75 FFAR1 (0.52) MAPTL3MBTL1CASP1LMNAKMT2A
SCHEMBL9632354 0.75 MAPT (0.51) MAPTL3MBTL1SMN1; SMN2RAB9AGLA
SCHEMBL9163588 0.74 LMNA (0.47) CASP1SMN1; SMN2HTTRAB9AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5082860-A Insecticides CIBA-GEIGY CORPORATION (US) 1992-01-21 US disclosed
US-5077311-A Ethyl 2-(3,5-difluorophenoxy)phenoxyethyl carbamate CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed