Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088398 | 0.85 | KMT2A (0.74) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL9548136 | 0.85 | KMT2A (0.74) | KMT2AALDH1A1KDM4EPTGS2HPGD | |
| SCHEMBL3102512 | 0.80 | KMT2A (0.65) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL5813440 | 0.79 | KMT2A (0.64) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL5812232 | 0.79 | KMT2A (0.62) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL3100957 | 0.79 | KMT2A (0.64) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL5812763 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL5815362 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL5818777 | 0.77 | KMT2A (0.60) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 | |
| Fr-122047 SCHEMBL9548128 | 0.76 | PTGS2 (1.00) | KMT2AALDH1A1KDM4ECYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |