Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | STK10 | O94804 | 4/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506330 | 0.82 | MAOA (0.51) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL16628857 | 0.81 | MAOA (0.41) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL262473 | 0.79 | GSK3B (0.50) | KCNA5ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11077691 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL427290 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL29674513 | 0.78 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL28812042 | 0.78 | MAOA (0.59) | HPGDMAOAMAOBSMN1; SMN2MEN1 | |
| SCHEMBL30830771 | 0.77 | HTR2A (0.42) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL9768590 | 0.76 | KDM4E (0.51) | KCNA5ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL11908954 | 0.76 | ADORA2A (0.49) | ALDH1A1KDM4ELMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216173-A | Curing agents for epoxy resins; polyimides | HENKEL RESEARCH CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1991001307-A2 | N-CYANOIMIDES AND PROCESS FOR THEIR PREPARATION AND USES THEREOF | HENKEL RESEARCH CORPORATION (US) | 1991-02-07 | — | — | WO | disclosed |