SCHEMBL482108

SCHEMBL482108

[N-]=[N+]=C1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPK1 P28482 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
S100A4 P26447 2/20 0.38
NPC1 O15118 2/20 0.38
MAOA P21397 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CES2 O00748 1/20 0.38
APAF1 O14727 1/20 0.38
TERT O14746 1/20 0.38
PLIN1 O60240 1/20 0.38
TDP2 O95551 1/20 0.38
S1PR4 O95977 1/20 0.38
PLA2G1B P04054 1/20 0.38
BCHE P06276 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29394495 1.00 MEN1 (0.38) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8994826 0.92 SMN1; SMN2 (0.33) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8936666 0.84 MEN1 (0.60) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL3888093 0.83 ALDH1A1 (0.46) MAPK1LMNAMAPTALDH1A1L3MBTL1
SCHEMBL482129 0.82 S100A4 (0.55) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8076780 0.82 SMN1; SMN2 (0.37) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8076772 0.82 SMN1; SMN2 (0.37) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL10425615 0.80 GPR3 (0.41) PTPRCL3MBTL1CYP1A2GPR3
SCHEMBL10426587 0.80 S100A4 (0.52) MEN1KMT2ASMN1; SMN2S100A4NPC1
SCHEMBL8964577 0.77 S100A4 (0.48) MEN1KMT2AMAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850256-A Diazafluorene compound, material for organic electroluminescent device and organic electroluminescent device 东莞伏安光电科技有限公司 2023-03-28 CN claimed
US-20220162649-A1 NOVEL NUCLEIC ACID MODIFIERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-26 US claimed
US-20210214724-A1 NOVEL NUCLEIC ACID MODIFIERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-07-15 US claimed
WO-2020206036-A1 NOVEL NUCLEIC ACID MODIFIER THE BROAD INSTITUTE, INC. (US) 2020-10-08 WO claimed
US-20200190011-A1 Reagents and Methods for Esterification WISCONSIN ALUMNI RESEARCH FOUNDATION 2020-06-18 US claimed
US-10577303-B1 Reagents and methods for esterification WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-03-03 US claimed
CN-110854283-A Structure for realizing medium-high frequency alternating current drive OLED by using TADF 福州大学 2020-02-28 CN claimed
WO-2019135816-A9 NOVEL NUCLEIC ACID MODIFIERS THE BROAD INSTITUTE, INC. (US) 2019-10-17 WO claimed
WO-2019135816-A2 NOVEL NUCLEIC ACID MODIFIERS THE BROAD INSTITUTE, INC. (US) 2019-07-11 WO claimed
US-10258695-B2 Protein derivatization to endow cell penetration WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-04-16 US claimed
US-9650374-B2 Photochromic tetrahydroindolizines UMM AL-QURA UNIVERSITY (SA) 2017-05-16 US claimed
WO-2016067069-A1 NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES UMM AL-QURA UNIVERSITY (SA) 2016-05-06 WO claimed
US-20160122338-A1 NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES UMM AL-QURA UNIVERSITY (SA) 2016-05-05 US claimed
US-20160067342-A1 PROTEIN DERIVATIZATION TO ENDOW CELL PENETRATION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-10 US claimed
US-12604650-B2 Method for manufacturing light-emitting element and light-emitting device using photolithography technique SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-04-14 US disclosed
US-20260015543-A1 Organometallic Complex and Light-Emitting Device SEMICONDUCTOR ENERGY LAB (JP) 2026-01-15 US disclosed
EP-3898706-B1 PROCESS FOR PREPARING HNBR SOLUTIONS WITH ALTERNATIVE SOLVENTS ARLANXEO DEUTSCHLAND GMBH (DE) 2025-10-01 EP disclosed
US-4122113-A 9-Fluorenyl acrylates XEROX CORPORATION (US) 1978-10-24 US disclosed
US-4098984-A ELECTRON ACCEPTOR POLYMERS XEROX CORPORATION (US) 1978-07-04 US disclosed
US-4046564-A ELECTROPHOTOGRAPHIC IMAGING MEMBERS WITH PHOTOCONDUCTIVE LAYER CONTAINING ELECTRON ACCEPTOR MONOMERS OR POLYMERS XEROX CORPORATION (US) 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190011-A1 Reagents and Methods for Esterification ADCY1, ADCY4, ADCY7 MEN1 723/4885KMT2A 2740/4885MAPK1 701/4885
US-20260015543-A1 Organometallic Complex and Light-Emitting Device CRY1, CRY2, SCO2 MEN1 494/4885KMT2A 1311/4885MAPK1 3991/4885
US-20160067342-A1 PROTEIN DERIVATIZATION TO ENDOW CELL PENETRATION PHAX, FIBP, TIA1 MEN1 1518/4885KMT2A 3077/4885MAPK1 4145/4885
US-20210214724-A1 NOVEL NUCLEIC ACID MODIFIERS DCLRE1A, MRE11, DDB1 MEN1 2631/4885KMT2A 935/4885MAPK1 4106/4885
US-20160122338-A1 NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES DHPS, TPH2, DHX15 MEN1 4240/4885KMT2A 1693/4885MAPK1 2101/4885
US-10577303-B1 Reagents and methods for esterification ADCY1, ADCY4, ADCY7 MEN1 723/4885KMT2A 2740/4885MAPK1 701/4885
US-12604650-B2 Method for manufacturing light-emitting element and light-emitting device using photolithography technique ASIC1, ASIC3, CA1 MEN1 574/4885KMT2A 2453/4885MAPK1 34/4885
US-10258695-B2 Protein derivatization to endow cell penetration PHAX, FIBP, TIA1 MEN1 1518/4885KMT2A 3077/4885MAPK1 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.