Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL25313540 | 0.96 | TSHR (0.43) | — | |
| Potassium Ion SCHEMBL31202579 | 0.93 | TSHR (0.46) | — | |
| SCHEMBL29973212 | 0.93 | TSHR (0.46) | — | |
| SCHEMBL12274283 | 0.93 | TSHR (0.46) | — | |
| Potassium Ion SCHEMBL17113317 | 0.93 | TSHR (0.46) | — | |
| SCHEMBL74117 | 0.93 | — | — | |
| SCHEMBL27616519 | 0.93 | TSHR (0.46) | — | |
| Potassium Ion SCHEMBL37894 | 0.93 | — | — | |
| Potassium Ion SCHEMBL3888413 | 0.93 | TSHR (0.46) | — | |
| SCHEMBL31161204 | 0.89 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9068119-B2 | Method for producing mono-hydroxy-functionalized dialkylphosphinic acids, esters and salts using a vinyl ester of a carobxylic acid and the use thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-06-30 | — | — | US | claimed |
| US-7871708-B2 | Metal and polymer substrates having a powder basecoat and liquid topcoat | PPG INDUSTRIES OHIO, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-20060188735-A1 | a steel or polymeric (e.g. polyethylene) substrate, a base coat deposited on the substrate made of a thermosettable polyester, a curing agent ( e.g N,N,N',N'-tetrakis(2-hydroxyethyl) adipamide); a reaction product of decene, maleic anhydride and monoethanolamine; flow control agent; a topcoat | PPG INDUSTRIES OHIO, INC. | 2006-08-24 | — | — | US | disclosed |