Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554635 | 0.77 | LTA4H (0.42) | — | |
| SCHEMBL9554926 | 0.72 | LTA4H (0.37) | POLBMAPT | |
| SCHEMBL9727512 | 0.68 | MME (0.47) | — | |
| SCHEMBL7153646 | 0.67 | TDP1 (0.39) | POLBMAPTTDP1 | |
| SCHEMBL6710716 | 0.67 | TDP1 (0.39) | POLBMAPTTDP1 | |
| SCHEMBL7379297 | 0.66 | ACE (0.48) | POLBMAPTTDP1 | |
| SCHEMBL7269757 | 0.66 | BIRC2 (0.49) | — | |
| SCHEMBL31690300 | 0.65 | CYP1A2 (0.61) | — | |
| SCHEMBL9320151 | 0.65 | TPSAB1 (0.43) | POLBMAPTTDP1 | |
| SCHEMBL7196919 | 0.64 | L3MBTL1 (0.39) | POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134123-A | Renin enzyme inhibitors for cardiovascular disorders and high blood pressure | HOFFMAN-LA ROCHE INC. (US) | 1992-07-28 | — | — | US | disclosed |