Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 4/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556577 | 0.89 | LTA4H (0.37) | LTA4HHPGDGPR142CYP1A2PSMB11 | |
| SCHEMBL9556425 | 0.83 | LTA4H (0.43) | LTA4HGPR142FFAR2 | |
| SCHEMBL9556719 | 0.83 | LAP3 (0.33) | LTA4HHPGDGPR142FFAR2CYP1A2 | |
| SCHEMBL9556396 | 0.80 | LTA4H (0.41) | LTA4HGPR142FFAR2 | |
| SCHEMBL7354895 | 0.79 | HRH4 (0.43) | HPGDREN | |
| SCHEMBL9556548 | 0.78 | REN (0.35) | LTA4HGPR142FFAR2REN | |
| SCHEMBL9556729 | 0.77 | REN (0.44) | LTA4HREN | |
| SCHEMBL6209574 | 0.77 | CPA3 (0.47) | LTA4HHPGD | |
| SCHEMBL6209579 | 0.77 | CPA3 (0.47) | LTA4HHPGD | |
| SCHEMBL9556549 | 0.77 | REN (0.45) | HPGDPSMB5REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |