Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556717 | 0.85 | CTNNB1 (0.48) | CTNNB1FFAR1AKR1B1PARP10HRH4 | |
| SCHEMBL7353938 | 0.85 | CTNNB1 (0.48) | CTNNB1FFAR1AKR1B1PARP10HRH4 | |
| SCHEMBL10422428 | 0.80 | HRH4 (0.47) | PIN1HRH4 | |
| SCHEMBL10422431 | 0.79 | REN (0.51) | PIN1HRH4 | |
| SCHEMBL12812630 | 0.78 | PPARG (0.55) | FFAR1PPARGPTGESALOX5PPARA | |
| SCHEMBL6677809 | 0.77 | CTNNB1 (0.63) | CTNNB1HRH4KMT2AMEN1TDP1 | |
| SCHEMBL9556813 | 0.76 | PARP10 (0.51) | CTNNB1FFAR1AKR1B1PARP10PPARG | |
| SCHEMBL9556809 | 0.76 | PARP10 (0.51) | CTNNB1FFAR1AKR1B1PARP10PPARG | |
| SCHEMBL10870476 | 0.76 | TDP1 (0.47) | CTNNB1HRH4PPARGPTGESALOX5 | |
| SCHEMBL10522072 | 0.76 | HRH4 (0.50) | CTNNB1FFAR1AKR1B1HRH4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904660-A | HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |