Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557186 | 0.95 | NAAA (0.55) | RAB9ANPC1LMNATDP1DPP7 | |
| SCHEMBL9557043 | 0.92 | NPC1 (0.54) | RAB9ANPC1LMNATDP1DPP7 | |
| SCHEMBL9556995 | 0.86 | SIGMAR1 (0.40) | RAB9ANPC1DPP7 | |
| SCHEMBL9556903 | 0.86 | MAOA (0.51) | NPC1LMNANAAAALDH1A1ME2 | |
| SCHEMBL9556940 | 0.86 | NAAA (0.48) | NAAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9557168 | 0.86 | NPC1 (0.54) | RAB9ANPC1TDP1NAAAKMT2A | |
| SCHEMBL9557028 | 0.84 | NAAA (0.58) | NAAAGRM5KMT2AMEN1MAPT | |
| SCHEMBL9557084 | 0.83 | MAOA (0.56) | RAB9ANPC1LMNATDP1NAAA | |
| SCHEMBL9557252 | 0.83 | MAOA (0.54) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL9557006 | 0.83 | NPC1 (0.42) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |