Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557047 | 0.91 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1MAPTALOX15 | |
| SCHEMBL9556940 | 0.85 | NAAA (0.48) | ALDH1A1AR | |
| SCHEMBL9557059 | 0.83 | RAB9A (0.51) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9556995 | 0.83 | SIGMAR1 (0.40) | NPC1RAB9AARTRPV1 | |
| SCHEMBL9556903 | 0.83 | MAOA (0.51) | NPC1ALDH1A1 | |
| SCHEMBL9557168 | 0.82 | NPC1 (0.54) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL9557252 | 0.82 | MAOA (0.54) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9557044 | 0.79 | NAAA (0.54) | TRPV1 | |
| SCHEMBL9557038 | 0.79 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL9557179 | 0.79 | MAOA (0.52) | NPC1RAB9AMAPTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |