Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557185 | 0.96 | MAOA (0.53) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557091 | 0.95 | MAOA (0.52) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557154 | 0.92 | FKBP1A (0.64) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557029 | 0.87 | FKBP1A (0.56) | FKBP1AKMT2AALDH1A1MEN1ALOX5 | |
| SCHEMBL9556940 | 0.85 | NAAA (0.48) | KMT2AALDH1A1MEN1CASP3CASP7 | |
| SCHEMBL9556995 | 0.83 | SIGMAR1 (0.40) | MAOASIGMAR1 | |
| SCHEMBL9557059 | 0.83 | RAB9A (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2HPGD | |
| SCHEMBL9556903 | 0.83 | MAOA (0.51) | MAOAALDH1A1ME2ME1ME3 | |
| SCHEMBL31329280 | 0.82 | FKBP1A (0.64) | FKBP1AKMT2AALDH1A1MEN1ALOX5 | |
| SCHEMBL31329327 | 0.82 | FKBP1A (0.64) | FKBP1AKMT2AALDH1A1MEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |