Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557091 | 0.99 | MAOA (0.52) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557252 | 0.96 | MAOA (0.54) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557154 | 0.91 | FKBP1A (0.64) | MAOAMAOBFKBP1AKMT2AALDH1A1 | |
| SCHEMBL9557029 | 0.91 | FKBP1A (0.56) | FKBP1AKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9557038 | 0.83 | TRPV1 (0.43) | MAOBSIGMAR1 | |
| SCHEMBL9557044 | 0.83 | NAAA (0.54) | MAOA | |
| SCHEMBL9557179 | 0.83 | MAOA (0.52) | MAOASIGMAR1 | |
| SCHEMBL9557015 | 0.82 | NAAA (0.53) | MAOA | |
| SCHEMBL9557186 | 0.82 | NAAA (0.55) | — | |
| SCHEMBL9556940 | 0.82 | NAAA (0.48) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |