Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ME2 | P23368 | 1/20 | 0.52 |
| ▸ | ME1 | P48163 | 1/20 | 0.52 |
| ▸ | ME3 | Q16798 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557252 | 0.92 | MAOA (0.54) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9557185 | 0.91 | MAOA (0.53) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9557091 | 0.90 | MAOA (0.52) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9557104 | 0.85 | ALDH1A1 (0.49) | FKBP1AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL9557043 | 0.82 | NPC1 (0.54) | FKBP1AALDH1A1KMT2AMEN1ME2 | |
| SCHEMBL10305162 | 0.81 | FKBP1A (0.76) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9557029 | 0.81 | FKBP1A (0.56) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9557069 | 0.80 | MC4R (0.47) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14218027 | 0.77 | FKBP1A (0.69) | FKBP1AALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9556940 | 0.77 | NAAA (0.48) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198450-A | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND USAGE OF THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0424528-A1 | PHENYLALKANOYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |