Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557291 | 0.88 | TP53 (0.38) | CTSDTP53SMN1; SMN2GAANPC1 | |
| SCHEMBL9557493 | 0.85 | CTSD (0.44) | CTSDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL9557683 | 0.83 | CTSD (0.49) | CTSDTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9714336 | 0.80 | SMN1; SMN2 (0.48) | CTSDSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL9714340 | 0.80 | ABCB1 (0.49) | SMN1; SMN2HPGD | |
| SCHEMBL9557474 | 0.73 | CES2 (0.56) | SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9557760 | 0.73 | POLB (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9558110 | 0.73 | ALDH1A1 (0.44) | CTSDTP53SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL10779145 | 0.73 | CTSD (0.39) | CTSDNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9557846 | 0.72 | CTSD (0.46) | CTSDTP53SMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |