Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.56 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841545 | 0.90 | ITGB3 (0.53) | MAPK1ITGB3ITGA2BYAP1P2RX7 | |
| SCHEMBL9558243 | 0.87 | YAP1 (0.64) | MAPK1YAP1P2RX7ACE | |
| SCHEMBL7276592 | 0.85 | POLB (0.65) | MAPK1YAP1ACE | |
| SCHEMBL7276597 | 0.85 | POLB (0.65) | MAPK1YAP1ACE | |
| SCHEMBL6349585 | 0.82 | P2RX7 (0.73) | MAPK1YAP1P2RX7 | |
| SCHEMBL27841549 | 0.82 | YAP1 (0.52) | ITGB3ITGA2BYAP1P2RX7HRH2 | |
| SCHEMBL27841551 | 0.82 | YAP1 (0.52) | ITGB3ITGA2BYAP1P2RX7HRH2 | |
| SCHEMBL6165579 | 0.80 | MAPK1 (0.75) | MAPK1YAP1 | |
| SCHEMBL6165580 | 0.80 | MAPK1 (0.75) | MAPK1YAP1 | |
| SCHEMBL9558236 | 0.80 | MAPK1 (0.64) | MAPK1YAP1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215968-A | Hypotension agents and viricides | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0373497-A2 | Dipeptide derivatives with an enzyme-inhibiting activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |