Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878676 | 0.81 | TAAR1 (0.38) | SMN1; SMN2HTTRAB9ATAAR1ADRA2A | |
| SCHEMBL9558559 | 0.78 | HPGD (0.38) | SMN1; SMN2RAB9AHPGDTAAR1ADRA2A | |
| SCHEMBL9558609 | 0.78 | HPGD (0.38) | SMN1; SMN2RAB9AHPGDTAAR1ADRA2A | |
| SCHEMBL9744645 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2RAB9AHPGDTAAR1ADRA2A | |
| SCHEMBL24922344 | 0.74 | — | — | |
| SCHEMBL6983487 | 0.74 | POLB (0.41) | SMN1; SMN2RAB9AHPGDADRA2AADRA2B | |
| SCHEMBL15347875 | 0.74 | POLB (0.41) | SMN1; SMN2RAB9AHPGDADRA2AADRA2B | |
| SCHEMBL9557896 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2RAB9AHPGDTAAR1CYP2C19 | |
| SCHEMBL13946975 | 0.72 | HTT (0.40) | SMN1; SMN2HTTRAB9AHPGDTAAR1 | |
| SCHEMBL9558974 | 0.71 | SLC6A3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245835-B1 | NOVEL THIOPHENE DERIVATIVES AND METHODS FOR PRODUCING THE SAME | SEITETSU KAGAKU CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |