Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558559 | 1.00 | HPGD (0.38) | HPGDDPP4TAAR1ADRA2AADRA2B | |
| SCHEMBL9744645 | 0.87 | ALDH1A1 (0.38) | HPGDTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL9557896 | 0.84 | ALDH1A1 (0.45) | HPGDTAAR1RAB9ANPC1PLA2G1B | |
| SCHEMBL7878676 | 0.82 | TAAR1 (0.38) | DPP4TAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL9558342 | 0.78 | SMN1; SMN2 (0.40) | HPGDTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL6983491 | 0.78 | CYP2C19 (0.42) | HPGDRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL24922344 | 0.76 | — | — | |
| SCHEMBL6983487 | 0.76 | POLB (0.41) | HPGDADRA2AADRA2BADRA2CRAB9A | |
| SCHEMBL15347875 | 0.76 | POLB (0.41) | HPGDADRA2AADRA2BADRA2CRAB9A | |
| SCHEMBL10796125 | 0.73 | TAAR1 (0.39) | HPGDDPP4TAAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245835-B1 | NOVEL THIOPHENE DERIVATIVES AND METHODS FOR PRODUCING THE SAME | SEITETSU KAGAKU CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |