Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557896 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL9558609 | 0.87 | HPGD (0.38) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL9558559 | 0.87 | HPGD (0.38) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL7878676 | 0.80 | TAAR1 (0.38) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL9558342 | 0.75 | SMN1; SMN2 (0.40) | ALDH1A1TSHRRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6983491 | 0.75 | CYP2C19 (0.42) | ALDH1A1NPC1RAB9APOLBMEN1 | |
| SCHEMBL24922344 | 0.73 | — | — | |
| SCHEMBL15347875 | 0.73 | POLB (0.41) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL6983487 | 0.73 | POLB (0.41) | ALDH1A1TSHRNPC1RAB9APOLB | |
| SCHEMBL7966776 | 0.73 | PPARG (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101049-A | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |
| US-4792612-A | MEDICINE INTERMEDIATES | SEITETSU KAGAKU CO., LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0245835-A2 | Novel thiophene derivatives and methods for producing the same | SEITETSU KAGAKU CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |