Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477061 | 0.82 | ESR1 (0.54) | PLK1CYP3A4S1PR2S1PR4S1PR1 | |
| SCHEMBL7651565 | 0.82 | NPSR1 (0.54) | PLK1CYP3A4GAAKMT2AMEN1 | |
| SCHEMBL3426470 | 0.81 | PLK1 (0.61) | PLK1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20723944 | 0.79 | MAPT (0.58) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10931913 | 0.79 | SPHK1 (0.58) | PLK1CYP3A4S1PR2S1PR4S1PR1 | |
| SCHEMBL259701 | 0.79 | MAPT (0.65) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1033939 | 0.78 | NPSR1 (0.58) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20197373 | 0.77 | MAPT (0.71) | PLK1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13093956 | 0.77 | FFAR1 (0.57) | PLK1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21241028 | 0.77 | MAPT (0.64) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293942-B1 | LIQUID CRYSTAL COMPOSITION CONTAINING A PLEOCHROIC AZO TYPE COMPOUND | MITSUBISHI KASEI CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4959172-A | Liquid crystal composition containing a pleochroic azo type compound | MITSUBISHI KASEI CORPORATION (JP) | 1990-09-25 | — | — | US | disclosed |
| EP-0293942-A2 | Liquid crystal composition containing a pleochroic azo type compound | MITSUBISHI KASEI CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |