Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.51 |
| ▸ | CES1 | P23141 | 5/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL18684847 | 0.93 | CES2 (0.54) | CA2CA4CES2CES1NAAA | |
| Benzoic Acid SCHEMBL28696691 | 0.93 | CA2 (0.52) | CA2CA4CES2CES1CNR2 | |
| Terephthalic Acid SCHEMBL6632223 | 0.91 | BDKRB2 (0.49) | CA2BDKRB2MAPT | |
| Benzoic Acid SCHEMBL1036838 | 0.89 | CA2 (0.59) | CA2CA4CES2CES1NAAA | |
| Isophthalic Acid SCHEMBL2472673 | 0.88 | SMN1; SMN2 (0.47) | CA2CA4CES2CES1BDKRB2 | |
| Butyltriphenylphosphonium SCHEMBL7871063 | 0.85 | CA2 (0.50) | CA2CA4CES2CES1CNR2 | |
| Benzoic Acid SCHEMBL7615296 | 0.84 | CA2 (0.53) | CA2CA4CES2CES1NAAA | |
| Benzoic Acid SCHEMBL1685233 | 0.84 | CA2 (0.42) | CA2CA4CES2CES1CNR2 | |
| Phthalic Acid SCHEMBL5048545 | 0.84 | ALDH1A1 (0.47) | CA2CES2CES1CNR2PRSS1 | |
| Benzoic Acid SCHEMBL8725785 | 0.83 | CES2 (0.54) | CA2CA4CES2CES1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11945909-B2 | Process for preparing polycarbonates using a catalyst system having a quarternary nitrogen compond and a quarternary phosphorous compound | EPC Engineering & Technologies GmbH (DE) | 2024-04-02 | — | — | US | claimed |
| EP-3526274-B1 | CATALYST SYSTEM | EPC ENGINEERING & TECH GMBH (DE) | 2022-08-03 | — | — | EP | claimed |
| CN-114149391-A | Method for alcoholysis polymerization of 2, 5-furan diformate | 中国科学院大连化学物理研究所 | 2022-03-08 | — | — | CN | claimed |
| US-9206320-B1 | Matte-appearance powder coating compositions with chemical agent resistance | HENTZEN COATINGS, INC. (US) | 2015-12-08 | — | — | US | claimed |
| EP-1680806-A4 | CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME | SACHEM INC (US) | 2008-07-30 | — | — | EP | claimed |
| US-7192910-B2 | Cleaning solutions and etchants and methods for using same | SACHEM, INC. (US) | 2007-03-20 | — | — | US | claimed |
| EP-1680806-A2 | CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME | Sachem, Inc. (US) | 2006-07-19 | — | — | EP | claimed |
| US-20050143270-A1 | Cleaning solutions and etchants and methods for using same | SACHEM, INC. | 2005-06-30 | — | — | US | claimed |
| WO-2005045895-A2 | CLEANING SOLUTIONS AND ETCHANTS AND METHODS FOR USING SAME | SACHEM, INC. (US) | 2005-05-19 | — | — | WO | claimed |
| EP-0671428-B1 | Method for making polycarbonates | GEN ELECTRIC (US) | 2002-08-21 | — | — | EP | claimed |
| EP-0671428-A1 | Method for making polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1995-09-13 | — | — | EP | claimed |
| US-5412061-A | Polycarbonate melt condensation synthesis using a tetraorganophosphonium carboxylate salt catalyst | GENERAL ELECTRIC COMPANY (US) | 1995-05-02 | — | — | US | claimed |
| JP-7309939-A | — | — | None | — | — | JP | disclosed |
| US-20260071095-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2026-03-12 | — | — | US | disclosed |
| CN-120021421-A | Method and apparatus for improving flexibility and robustness of polycarbonate plants using pre-transesterification technology | EPC工程与技术有限公司 | 2025-05-20 | — | — | CN | disclosed |
| WO-2025061256-A1 | REACTORS AND THEIR SPECIAL DESIGN SUITABLE FOR A HIGH FLEXIBLE AND ROBUST POLYCARBONATE PLANT, IN PARTICULAR BY MEANS OF A PRE-TRANSESTERIFICATION TECHNOLOGY | EPC Engineering & Technologies GmbH (DE) | 2025-03-27 | — | — | WO | disclosed |
| US-4558072-A | RUTHENIUM AND MANGENESE COMPOUNDS DISPERSED IN PHOSPHONIUM COMPOUND | TEXACO INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4518715-A | Process for producing ethylene glycol using a ruthenium-copper catalyst | TEXACO INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4396726-A | Process for preparing ethylene glycol and lower monohydric alcohols from syn gas using a novel catalyst system | TEXACO INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4324885-A | QUATERNARY AMMONIUM OR PHOSPHONIUM CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071095-A1 | POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | PIEZO1, ZAP70, CAPN1 | CA2 695/4885CA4 634/4885CES2 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.