SCHEMBL9560149

SCHEMBL9560149

Cc1cc(Br)c(O)c(CO)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.45
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
AMY1A P0DUB6 1/20 0.39
HSPA5 P11021 1/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
SELE P16581 1/20 0.39
HIF1A Q16665 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68683 0.86 AMY1A (0.53) SHBGCA1CA2CA4CA6
SCHEMBL187792 0.85 SHBG (0.52) SHBGCA2AMY1AHSPA5SELL
SCHEMBL286765 0.82 SHBG (0.36) SHBGAMY1AHSPA5HIF1ACYP2C9
SCHEMBL1502445 0.80 CYP3A4 (0.58) CA1CA2CA4CA6CYP3A4
SCHEMBL14008500 0.79 SELL (0.59) SHBGAMY1AHSPA5SELLSELP
SCHEMBL866775 0.79 SHBG (0.63) SHBGCA1CA2AMY1AHSPA5
SCHEMBL1482608 0.79 AMY1A (0.61) SHBGCA2AMY1AHSPA5SELL
SCHEMBL30558172 0.79 SHBG (0.63) SHBGCA1CA2AMY1AHSPA5
SCHEMBL210506 0.79 AMY1A (0.61) SHBGCA2AMY1AHSPA5SELL
SCHEMBL31530705 0.79 SELL (0.59) SHBGAMY1AHSPA5SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287328-B1 PREPARATION OF CHROMOGENIC CRYPTAHEMISPHERANDS Bayer Corporation (US) 1993-10-06 EP disclosed
EP-0287328-A2 Preparation of chromogenic cryptahemispherands Bayer Corporation (US) 1988-10-19 EP disclosed